Inflammatory bowel disease linked to elevated risk of psychiatric disorders

Timeline of risk: Risk of psychiatric illness rises two–three years before IBD diagnosis, peaks within the first six months (a 50% increase), and stays elevated at 10 years (a 19% increase).
Main conditions: The risk increase was largely driven by major depressive disorder, anxiety disorders, and substance misuse.
Drug prescriptions: Prescriptions for antidepressants and anxiolytics increased a year before diagnosis and remained elevated for at least five years post-diagnosis.
Impact across subtypes: Results were consistent across Crohn's disease, ulcerative colitis, and unclassified IBD, with absolute risks highest in patients with childhood-onset IBD and those with a family history of psychiatric conditions.

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