Titans vs. Colts odds, picks, spread, how to watch, live stream: Model reveals 2024 Week 6 NFL predictions

SportsLine simulated Tennessee Titans vs. Indianapolis Colts in Week 6 of the 2024 NFL season 10,000 times

The Indianapolis Colts (2-3) visit the Tennessee Titans (1-3) for an AFC South rivalry in a Week 6 NFL battle on CBS and Paramount+. The Colts have played better since Joe Flacco stepped in for an injured Anthony Richardson, and the veteran signal caller will start again on Sunday. Meanwhile, the Titans were off in Week 5 after getting their first win of the season, a 31-12 victory against the Miami Dolphins. You may be able to stream Sunday's game live on Paramount+, which you can now try free for the first seven days when you sign up here.

Kickoff from Nissan Stadium in Nashville is set for 1 p.m. ET. The Titans are 2.5-point favorites in the latest Titans vs. Colts odds via SportsLine consensus, and the over/under for total points scored is 42.5. Sunday's game will be streamed live on Paramount+ with their must-have Paramount+ with SHOWTIME plan, which you can now get on a 7-day free trial.

Paramount+ is the only place to watch every minute of every NFL on CBS game this season. A subscription also gives you access to other sports content including the UEFA Champions League and Europa League, NWSL, Serie A, and countless movies and shows. You can now get a free 7-day trial, so sign up right here. 

How to watch Colts vs. Titans

• Titans vs. Colts date: Sunday, Oct. 13
• Titans vs. Colts time: 1 p.m. ET
• Titans vs. Colts TV channel: CBS 
• Titans vs. Colts streaming: Paramount+ 

Week 6 NFL picks for Colts vs. Titans

Before tuning into Sunday's Titans vs. Colts game, you need to see the NFL picks from SportsLine's advanced computer model. The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.

For Titans vs. Colts, the model is backing Tennessee to cover the spread at home. The Colts will be without superstar running back Jonathan Taylor due to an ankle injury on Sunday. Taylor has already racked up 349 rushing yards and four rushing touchdowns, so his absence will certainly be felt. 

The Titans feature the NFL's top-ranked defense this season, giving up just 243.8 yards per game. They've been especially stout against the pass, ranking first in the league in passing yards allowed per game (124.0). Plus, the Titans are 5-2 against the spread in their past seven meetings against the Colts, a trend the model expects to continue on Sunday. The model is backing Tennessee to cover the spread in over 50% of simulations. You may be able to stream the game here.

How to watch, live stream the NFL on CBS

Now that you know what to pick, get ready to watch your live local NFL on CBS games on Paramount+ on any device you want. Don't forget you can now try Paramount+ free for the first week.