Oklahoma State vs. BYU prediction, odds, spread: 2024 college football picks, Friday bets from proven model

SportsLine's model simulated Friday's BYU Cougars vs. Oklahoma State Cowboys matchup 10,000 times

The No. 13-ranked BYU Cougars will look to stay atop the Big 12 standings when they battle last season's conference runner-up Oklahoma State Cowboys on Friday night in a key matchup in Provo, Utah. The Cougars (6-0, 3-0 Big 12), who are off to their best start since 2020, have already surpassed last year's win total when they finished 2-7 in conference and 5-7 overall. The Cowboys (3-3, 0-3 Big 12), who are 0-2 against ranked opponents this season, have won all three previous meetings with BYU, including a 40-34 double-overtime win last year.

Kickoff from LaVell Edwards Stadium is set for 10:15 p.m. ET. After opening at -6.5, the Cougars are now favored by 9.5 points in the latest Oklahoma State vs. BYU odds, while the over/under for total points scored is 52.5. Before making any BYU vs. Oklahoma State picks, check out the college football predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 12-5 on all top-rated picks over the past three weeks of this season. Anyone who has followed it has seen strong returns on betting sites.

The model has set its sights on Oklahoma State vs. BYU. You can head to SportsLine to see its picks. Here are several college football betting lines and trends for BYU vs. Oklahoma State:

• Oklahoma State vs. BYU spread: BYU -9.5
• Oklahoma State vs. BYU over/under: 52.5 points
• Oklahoma State vs. BYU money line: BYU -360, Oklahoma State +278
• OSU: 1-4 ATS this season against FBS competition 
• BYU: 5-0 ATS this season against FBS competition 
• Oklahoma State vs. BYU picks: See picks at SportsLine
• Oklahoma State vs. BYU streaming: FuboTV (Try for free)

Why you should back BYU

Senior wide receiver Darius Lassiter is among the Cougars' top pass catchers. He has 21 receptions for 321 yards (15.3 average) and three touchdowns. Lassiter had five catches for 86 yards (17.2 average), including a long of 38 yards in the 41-19 win over Arizona on Saturday. He had eight receptions for 120 yards (15 average) and one touchdown in a 34-28 win at Baylor on Sept. 28.

Redshirt junior linebacker Jack Kelly has been a beast on defense. In six games this year, he has registered a team-high three sacks and 21 tackles, including 11 solo, with five tackles for loss. He has also forced one fumble, has seven quarterback hits and has broken up one pass. The transfer from Weber State has played in 34 career games, registering 105 tackles, including 61 solo, with 25 tackles for loss, 19.5 sacks, six forced fumbles, eight pass breakups and one interception. See which team to pick here.

Why you should back Oklahoma State

Redshirt senior quarterback Alan Bowman, in his second year with the program, has been under center for most of the season, but the Cowboys are reportedly eyeing a change, potentially giving sophomore Garret Rangel a chance in this one. Rangel has appeared in relief three times this season, completing 11 of 24 attempts for 141 yards and one touchdown. 

Junior running back Ollie Gordon II is one of most talented backs in the nation, but hasn't found his groove yet. For the season, he has 101 carries for 384 yards (3.8 average) and four touchdowns and Oklahoma State is hoping for a breakout game. See which team to pick here.

How to make Oklahoma State vs. BYU picks

SportsLine's model is leaning Over on the total, projecting 55 combined points. It also says one side of the spread hits well over 60% of the time. You can only get the pick at SportsLine.

So who wins Oklahoma State vs. BYU, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on its FBS college football picks since its inception, and find out.