Oregon vs. Purdue prediction, odds, line: 2024 Week 8 college football picks, Friday bets by proven model

SportsLine's model revealed its CFB picks and predictions for Purdue Boilermakers vs. No. 2 Oregon Ducks on Friday

Teams on opposite ends of the Big Ten standings face off on Friday when the No. 2 Oregon Ducks (6-0, 3-0) visit the Purdue Boilermakers (1-5, 0-3). Oregon stayed perfect after defeating its toughest opponent yet in Week 7, holding off the No. 3 Ohio State Buckeyes 32-31 to stay perfect on the season. The Ducks visit a Purdue side that almost won its second game of the season in Week 7, but ultimately fell 50-49 to No. 22 Illinois in overtime.

Kickoff from Ross-Ade Stadium is scheduled for 8 p.m. ET. The Ducks are 29.5-point favorites in the latest Oregon vs. Purdue odds from SportsLine consensus, while the over/under for total points scored is 61, up 2.5 points from the opening line. This is both the largest spread and the highest total on the Friday college football odds board. Before making any Purdue vs. Oregon picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks and it is 12-5 on top-rated picks over the past three weeks of this season. Anyone who has followed it on betting sites has seen strong returns.

Now, the model has dialed in on Purdue vs. Oregon and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football betting lines and trends for Oregon vs. Purdue.

• Purdue vs. Oregon spread: Ducks -29.5
• Purdue vs. Oregon over/under: 61 points 
• Purdue vs. Oregon money line: Ducks -7692, Boilermakers +1796
• Purdue: 2-4-0 ATS this season 
• Oregon: 2-4-0 ATS this season 
• Purdue vs. Oregon picks: See picks here
• Purdue vs. Oregon streaming: FuboTV (Try for free)

Why Purdue can cover

The Boilermakers will try to take advantage of an Oregon side that is coming down from a very emotional Big Ten game and travelling on short rest. Big Ten teams are 4-9 ATS and 3-10 straight up when travelling at least two time zones this season, which the Ducks will be doing less than a week after beating the Buckeyes by just one point.

Purdue is also coming off of one of its stronger performances of the season despite losing in overtime. The Boilermakers rallied out of a 12-point hole late in the fourth quarter against the Fighting Illini in Week 7 and held a three-point lead with less than a minute left to play. Redshirt freshman Ryan Browne impressed in place of injured quarterback Hudson Card, throwing for 297 yards and three touchdowns while also rushing for a team-high 118 yards. See who to back at SportsLine.

Why Oregon can cover

The Oregon defense faced a tough task in limiting the Buckeyes in Week 7 and should have an easier time restricting the Purdue offense. Oregon defense ranks seventh in the Big Ten with 297.3 average yards allowed per game, while Purdue's offense ranks 14th in both average yards per game (340) and points per game (23.7).

Oregon also has a more experienced quarterback in Dillon Gabriel. The senior and Heisman Trophy hopeful has thrown at least two touchdowns in each of the Ducks' six wins this season and has eclipsed 300 passing yards twice. He threw for 341 yards with two touchdowns and no interceptions against the conference's top-ranked defense in Week 7 and is about to go up against the worst-ranked defense in Week 8. See who to back at SportsLine.

How to make Purdue vs. Oregon picks

SportsLine's model is leaning Under on the total, projecting 59 combined points. It also says one side of the spread hits in 60% of simulations. You can see the model's pick at SportsLine.

So who wins Oregon vs. Purdue, and which side of the spread hits 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.