Virginia Tech vs. Miami prediction, odds, line: 2024 college football picks, Week 5 best bets from top expert

SportsLine's Jimmie Kaylor revealed his Week 5 CFB picks, predictions and props for the Virginia Tech Hokies vs. Miami Hurricanes game at Hard Rock Stadium in Miami

ACC squads that have gone different directions thus far in 2024 meet in a spotlight game on Friday as the Miami Hurricanes hosts the Virginia Tech Hokies. The No. 7 Hurricanes are 4-0 with every win coming by at least 24 points. The Hokies, meanwhile, are 2-2 and have been upset twice, losing to Rutgers and Vanderbilt. Virginia Tech is 1-3 against the spread, while Miami has a 3-1 ATS mark.

Kickoff at Hard Rock Stadium is at 7:30 p.m. ET. The latest Miami vs. Virginia Tech odds via SportsLine consensus list the Hurricanes at -17.5, while the over/under is 54. Before making any Virginia Tech vs. Miami picks, you need to see the Week 5 college football predictions and betting advice from SportsLine's Jimmie Kaylor. 

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor destroyed the books in college football in 2023, netting a whopping 57.9 units while posting a 107-45-2 record. Anyone who followed his picks finished the season way up.

Now, Kaylor has dialed in on Miami vs. Virginia Tech on Friday and just revealed his picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds and betting lines on the spread, money line and over/under for Virginia Tech vs. Miami:

• Virginia Tech vs. Miami spread: Miami -17.5
• Virginia Tech vs. Miami over/under: 54 points 
• Virginia Tech vs. Miami money line: Miami -909, Virginia Tech +589
• Virginia Tech vs. Miami picks: See picks at SportsLine

Why Miami can cover

Quarterback Cam Ward is the Heisman favorite at +350 entering this matchup and Miami will likely use this game as a showcase for his campaign. The Houston transfer has thrown for 1,439 yards, 14 touchdowns and two interceptions, while adding 89 yards and a score on the ground. He's hit at least 300 yards of passing and three scores in every game, and another effort like that will give Miami a great chance to cover this large number.

Miami has also been elite on defense, giving up just 10.3 points per game thus far, the best mark in the ACC. Virginia Tech has struggled to move the ball, particularly through the air, making this a very challenging matchup for the road team. See which team to pick here. 

Why Virginia Tech can cover

The Hokies are massive underdogs in this matchup, and they can turn their season around with a strong performance on Friday night. Virginia Tech is coming off a disappointing showing against Rutgers, but the Hokies do have the talent to give the Hurricanes their toughest test of the season.

Virginia Tech will likely lean on its rushing attack that is currently averaging 188.8 yards per game. Running back Bhayshul Tuten leads the way with 67 carries for 391 yards and seven touchdowns. Quarterback Kyron Drones is raw as a passer, but his running ability will keep the Miami defense on its toes. Drones has thrown for 765 yards, four touchdowns and three interceptions, and rushed for 209 yards and two scores this season. See which team to pick here. 

How to make Virginia Tech vs. Miami picks

Kaylor has analyzed Miami vs. Virginia Tech from every angle and he's leaning Over on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

So who wins Virginia Tech vs. Miami on Friday, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the spread to jump on, all from the expert who profited $5,790 for $100 college football bettors in 2023, and find out.