NFL DFS Monday Night Football picks: Chiefs vs. Saints daily fantasy lineup advice for DraftKings, FanDuel

SportsLine expert Jimmie Kaylor shares his Week 5 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool for Saints vs. Chiefs on MNF

The Week 5 NFL schedule comes to a close with a cross-conference matchup on Monday Night Football with the Kansas City Chiefs (-5.5, 43) set to host the New Orleans Saints at GEHA Field at Arrowhead Stadium. Kickoff is at 8:15 p.m. ET. The NFL DFS player pool is headlined by Patrick Mahomes, Travis Kelce, Derek Carr, Alvin Kamara and Chris Olave. Each of those players will be popular MNF NFL DFS picks, but finding the DFS sleepers and top values will be the key to cashing on the Week 5 MNF DFS showdown slate.

Should you build your NFL DFS lineups and NFL DFS stacks around Kelce and Mahomes, or would it make more sense to target Carr and Kamara? Before locking in any NFL DFS lineups for Chiefs vs. Saints on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks on sites like DraftKings and FanDuel.

Kaylor hit on epic NFL DFS picks for SportsLine members throughout the 2022 and 2023 seasons. In 2022, he was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15. In 2023, he hit on Ja'Marr Chase's massive Week 5 performance (15 catches, 192 yards, three TDs), D.J. Moore's eight catches for 230 yards and three touchdowns in Week 14, and De'Von Anchane's breakout performance (233 total yards, four TD's) in Week 3. Anyone who followed his picks is way up.

This season, in the Sao Paulo game one of Kaylor's top picks was Green Bay wide receiver Jayden Reed, who caught four passes for 138 yards and a touchdown and rushed for 33 yards and a score, and James Cook, who scored three touchdowns on Thursday Night Football against the Dolphins. 

Now, Kaylor has turned his attention to Chiefs vs. Saints on Monday Night Football in Week 5 and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Saints vs. Chiefs on MNF

One of Kaylor's top NFL DFS picks for Monday Night Football is Kelce. The seven-time All-Pro selection has gotten off to a slow start in 2024, but he is coming off his best game of the season in Week 4. Kelce hauled in seven passes for 89 yards on nine targets in Kansas City's 17-10 win over the Los Angeles Chargers.

The Chiefs' wide receiver group has been decimated by injuries this season, with Rashee Rice (knee) and Hollywood Brown (shoulder) both on short-term IR, and Mecole Hardman (knee) listed as questionable. On top of that, the running backs room has been depleted with Clyde Edwards-Helaire (illness) doubtful and Isiah Pacheco (fibula) now on IR, paving the way for an increase in target share for Kelce. Week 5 could prove to be Kelce's first double-digit target game of the 2024 season.

Kaylor is also targeting Saints running back Alvin Kamara. The former Tennessee standout has gotten off to a fast start in 2024, and is on pace to have one of the most productive seasons of his career. In four games under new offensive coordinator Klint Kubiak, Kamara has rushed for 362 yards and five touchdowns, and caught 17 passes for 174 yards and a score. He had popped up on the Saints' injury report, but has been removed and will enter Monday without an injury designation. 

The Chiefs have played well on the defensive side of the ball this season, but Kamara's all-purpose ability makes him a fairly safe fantasy option in a depleted MNF player pool. Kamara has caught 75+ passes in five of his seven full NFL seasons, and he is on pace to finish around that number again in 2024. See who else Kaylor likes right here.

How to set Monday Night Football NFL DFS lineups, player pools

Kaylor is also targeting another undervalued player who could explode for huge numbers on Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's NFL DFS picks, at SportsLine. 

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Saints vs. Chiefs on Monday Night Football, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from an NFL DFS expert who won a prestigious millionaire maker tournament, and find out.