NFL DFS Monday Night Football picks, stacks: Chiefs vs. Saints fantasy lineup advice on DraftKings, FanDuel

SportsLine expert Jimmie Kaylor shares his Week 5 NFL DFS picks, sleepers, rankings, values, lineups and player pool for Saints vs. Chiefs on MNF

The NFL Week 5 schedule features a matchup between the New Orleans Saints and Kansas City Chiefs (-5.5, 43) on Monday Night Football. Kickoff at GEHA Field at Arrowhead Stadium is scheduled for 8:15 p.m. ET. The MNF NFL DFS player pool will be without wide receivers Rashee Rice (knee) and Hollywood Brown (shoulder), running back Isiah Pacheco (fibula), and tight end Taysom Hill (ribs), who are all on injured reserve. Kansas City quarterback Patrick Mahomes will be among the top NFL DFS picks for Monday Night Football, and tight end Travis Kelce will likely be his top target.

Should you build your NFL DFS stacks and NFL DFS lineups around Mahomes and Kelce? Other proven options for the MNF DFS slate include Derek Carr, Alvin Kamara, and Chris Olave. Before locking in any NFL DFS lineups for Chiefs vs. Saints on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks on sites like DraftKings and FanDuel.

Kaylor hit on epic NFL DFS picks for SportsLine members throughout the 2022 and 2023 seasons. In 2022, he was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15. In 2023, he hit on Ja'Marr Chase's massive Week 5 performance (15 catches, 192 yards, three TDs), D.J. Moore's eight catches for 230 yards and three touchdowns in Week 14, and De'Von Anchane's breakout performance (233 total yards, four TD's) in Week 3. Anyone who followed his picks is way up.

This season, in the Sao Paulo game one of Kaylor's top picks was Green Bay wide receiver Jayden Reed, who caught four passes for 138 yards and a touchdown and rushed for 33 yards and a score, and James Cook, who scored three touchdowns on Thursday Night Football against the Dolphins. 

Now, Kaylor has turned his attention to Chiefs vs. Saints on Monday Night Football in Week 5 and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Saints vs. Chiefs on MNF

One of Kaylor's top NFL DFS picks for Monday Night Football is Chiefs tight end Travis Kelce. The future Hall of Famer has gotten off to a relatively slow start to the season, and has yet to find the end zone in 2024. Kelce is, however, coming off his best performance of the season, hauling in seven passes for 89 yards in Kansas City's 17-10 win over the Los Angeles Chargers.

Kelce was already a security blanket for Patrick Mahomes, but he could be in for an even bigger role on Monday night with all of the injuries the Chiefs have had at the wide receiver position. Kelce could be in line for his first double-digit target game of the season, which very well could result in him being one of the top fantasy performers on MNF.

Kaylor is also targeting Saints running back Alvin Kamara. The former Tennessee standout has gotten off to a fast start in 2024, and is on pace to have one of the most productive seasons of his career. In four games under new offensive coordinator Klint Kubiak, Kamara has rushed for 362 yards and five touchdowns, and caught 17 passes for 174 yards and a score. He had popped up on the Saints' injury report, but has been removed and will enter Monday without an injury designation. 

The Chiefs have played well on the defensive side of the ball this season, but Kamara's all-purpose ability makes him a fairly safe fantasy option in a depleted MNF player pool. Kamara has caught 75+ passes in five of his seven full NFL seasons, and he is on pace to finish around that number again in 2024. See who else Kaylor likes right here.

How to set Monday Night Football NFL DFS lineups, player pools

Kaylor is also targeting another undervalued player who could explode for huge numbers on Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's NFL DFS picks, at SportsLine. 

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Saints vs. Chiefs on Monday Night Football, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from an NFL DFS expert who won a prestigious millionaire maker tournament, and find out.