Takeda Pharmaceutical (NYSE:TAK) Posts Earnings Results, Misses Estimates By $0.07 EPS

31 Jan 2026, 15:54 by Kim Johansen · The Markets Daily

Takeda Pharmaceutical (NYSE:TAK – Get Free Report) posted its quarterly earnings results on Thursday. The company reported $0.48 earnings per share (EPS) for the quarter, missing the consensus estimate of $0.55 by ($0.07), Zacks reports. The firm had revenue of $7.76 billion for the quarter, compared to analysts’ expectations of $7.81 billion. Takeda Pharmaceutical had a return on equity of 10.73% and a net margin of 2.58%.

Here are the key takeaways from Takeda Pharmaceutical’s conference call:

Takeda delivered three Phase‑3 wins—oveporexin, rusfertide and zasocitinib—has filed NDAs for the first two, is preparing the zasocitinib filing for 2027, and expects these launches over the next 18 months to be major growth drivers.
Management cut revenue guidance to a low single‑digit decline at CER due mainly to stronger‑than‑expected generic erosion of Vyvanse, which was the primary headwind to year‑to‑date revenue performance.
Operational cost discipline and lower R&D/SG&A allowed Takeda to maintain full‑year guidance for core operating profit and core EPS, and to upgrade adjusted free cash flow despite the Vyvanse headwind.
Entyvio showed strong Q3 growth and broader U.S. pen coverage (~80%), but its selection for IRA price negotiation introduces uncertainty around 2028 Medicare pricing and potential impact on long‑term peak sales.

Takeda Pharmaceutical Price Performance

TAK traded up $0.04 during midday trading on Friday, reaching $17.21. 5,626,273 shares of the company’s stock were exchanged, compared to its average volume of 3,160,032. Takeda Pharmaceutical has a 1-year low of $12.99 and a 1-year high of $17.25. The stock has a market capitalization of $54.76 billion, a PE ratio of 71.71 and a beta of 0.03. The company has a debt-to-equity ratio of 0.61, a current ratio of 1.37 and a quick ratio of 0.76. The business’s 50-day moving average price is $15.41 and its 200 day moving average price is $14.81.

Wall Street Analysts Forecast Growth

A number of equities research analysts have commented on TAK shares. Morgan Stanley began coverage on Takeda Pharmaceutical in a report on Tuesday, January 13th. They issued an “overweight” rating for the company. Weiss Ratings reiterated a “hold (c-)” rating on shares of Takeda Pharmaceutical in a research note on Monday, December 29th. Finally, Wall Street Zen raised shares of Takeda Pharmaceutical from a “hold” rating to a “strong-buy” rating in a report on Saturday. One equities research analyst has rated the stock with a Buy rating, one has assigned a Hold rating and one has assigned a Sell rating to the company. According to MarketBeat, the stock has an average rating of “Hold”.

Check Out Our Latest Stock Analysis on Takeda Pharmaceutical

Takeda Pharmaceutical News Roundup

Here are the key news stories impacting Takeda Pharmaceutical this week:

Positive Sentiment: Takeda raised FY‑2025 revenue guidance to $29.4 billion and issued EPS guidance of 3.160, above consensus revenue expectations — a clear near‑term positive for top‑line visibility and investor sentiment.
Positive Sentiment: Q3 results beat expectations: EPS $0.95 vs. $0.55 consensus; management cited cost discipline, FX tailwinds and narrowing gap between Growth & Launch products and VYVANSE generic erosion—management is tightening OPEX and raising confidence in the full‑year outlook. Takeda Reports Third-Quarter FY2025 Results
Neutral Sentiment: CEO Christophe Weber discussed succession planning and avoiding a ‘lame duck’ exit — governance and leadership continuity themes that reduce execution risk but are longer‑term in impact. Takeda’s Christophe Weber on avoiding a ‘lame duck’ succession
Neutral Sentiment: Earnings‑call and transcript detail product performance, launch timing and cost actions — useful for modeling but not an immediate catalyst. Takeda Q3 FY2025 Earnings Call Transcript
Negative Sentiment: Analyst downgrade from Buy to Hold after TAK hit 52‑week highs — valuation noted as less compelling and the lack of a clear Entyvio successor reduces near‑term upside; this can pressure sentiment and limit multiple expansion. Takeda Tests New Highs, But Struggles To Find Entyvio Successor
Negative Sentiment: Legal exposure: an adverse jury outcome in an Actos-related case and active litigation motions (including efforts to move a Louisiana suit) represent potential liabilities and headline risk that can weigh on the stock. Takeda and Eli Lilly fall foul of jury in Actos Pharma company wants La. suit over stomach acid meds moved

Institutional Inflows and Outflows

Institutional investors have recently modified their holdings of the stock. Northwestern Mutual Wealth Management Co. grew its holdings in Takeda Pharmaceutical by 56.3% during the 2nd quarter. Northwestern Mutual Wealth Management Co. now owns 3,586 shares of the company’s stock valued at $55,000 after buying an additional 1,292 shares during the last quarter. Advisory Services Network LLC acquired a new position in shares of Takeda Pharmaceutical in the third quarter worth $74,000. Larson Financial Group LLC lifted its position in shares of Takeda Pharmaceutical by 43.7% in the third quarter. Larson Financial Group LLC now owns 7,823 shares of the company’s stock valued at $115,000 after acquiring an additional 2,379 shares in the last quarter. B. Riley Wealth Advisors Inc. acquired a new stake in shares of Takeda Pharmaceutical during the second quarter valued at $174,000. Finally, BNP Paribas Financial Markets increased its position in Takeda Pharmaceutical by 1,652.2% during the 2nd quarter. BNP Paribas Financial Markets now owns 11,845 shares of the company’s stock worth $183,000 after purchasing an additional 11,169 shares in the last quarter. 9.17% of the stock is currently owned by institutional investors and hedge funds.

Takeda Pharmaceutical Company Profile

(Get Free Report)

Takeda Pharmaceutical Company Limited (NYSE: TAK) is a Tokyo-based, multinational biopharmaceutical company with roots dating back to 1781. The company researches, develops, manufactures and commercializes pharmaceutical and biopharmaceutical products for patients worldwide. Takeda is publicly listed and operates as a fully integrated R&D-driven healthcare company focused on delivering specialty medicines and therapies across a range of therapeutic areas.