Silica nanomatrix enhances immunotherapy for solid tumors

Professor Yung noted that the new material has the potential to extend beyond cancer treatment. He explained: "In the silica nanomatrix, dendritic cells adopt a distinctive Z-shaped morphology that increases their surface contact area, enabling more effective transmission of biophysical signals and setting them apart from conventionally cultured DCs. By harnessing biophysical cues instead of high-risk manipulations, our work offers a safer and more scalable pathway for DC vaccines. In future, we will explore the potential of these novel dendritic cells in systemic lupus erythematosus and multiple sclerosis, with the aim of opening up new directions for immunomodulatory therapies."

The research team plans to collaborate with hospitals and laboratories in Hong Kong and Mainland China to further accelerate cell culture protocols, evaluate therapeutic efficacy, and advance clinical research.

Source:

The Education University of Hong Kong