$2 million NIH funding supports wearable knee exoskeleton research

Building on the success of projects to boost strength by adding motors to conventional knee, hip and ankle braces, a University of Michigan team is exploring how well this approach could work for relieving knee pain from osteoarthritis.

"This could create an entirely new class of orthotic interventions that don't exist today, which could potentially delay surgery or spare people from having to undergo it," said Robert Gregg, U-M professor of robotics and leader of the project funded with $2 million from the National Institutes of Health.

In earlier work, exoskeletons, or exos, developed by Gregg's team reduced the effort expended by study participants by:

• 14.5% in quadriceps effort with knee exos
• 19.1% in lower ankle torque with ankle exos
• 25% in work done by the hip with hip exos

Robert Gregg, U-M professor of robotics and leader of the projectWe ran a pilot study with four people with knee osteoarthritis. They all experienced pain reduction. If you reduce peak muscle forces at the joint, you're reducing the peak loads of the contractile muscles that pull the joint together. You reduce that peak, and you reduce arthritic pain."

Reducing contact forces inside knee joints

Now, they will dig into musculoskeletal models to quantify how exo assistance reduces the bone-on-bone contact forces-and therefore the pain-inside arthritic joints. They will use this information to adapt the exo control algorithm to reduce contact forces rather than just muscle effort, and ultimately assess the effects on participants' self-reported pain across a variety of activities.

Earlier motors that were small enough to mount on knee braces needed more gears to provide higher torque. Gears are louder and harder to drive backward, resulting in exos that are stiff and noisy, similar in volume to a household drill. Pancake motors provide both the power and smooth operation needed for compatibility with human motion while being nearly silent.

Clinical trial with participants who have arthritis

While this study is a lab trial, Gregg hopes to eventually send exos home with users to see whether they reduce the vicious cycle of muscle wasting that accompanies osteoarthritis. Because exoskeletons make each step easier, muscle atrophy could get worse if users aren't moving more. The team is betting that if exo users can move with less pain, they will move more often, and increasing cumulative activity levels could strengthen the muscles of exo users.

Source:

University of Michigan