PCORI announces new funding for patient-centered clinical effectiveness research
· News-MedicalThe Patient-Centered Outcomes Research Institute (PCORI) today announced new funding to support patient-centered comparative clinical effectiveness research (CER) across a range of health conditions experienced by Americans, along with projects designed to help bring practice-changing CER results into real-world care settings.
Across the United States, people make decisions about their healthcare without always having clear information about the potential benefits and risks of different treatment options. These awards are part of PCORI's growing portfolio of funded research that produces information to help patients, caregivers and the broader healthcare community choose between care options - and to support projects that help integrate evidence into everyday care.
Funding highlights
- Thirteen new patient-centered CER studies addressing a range of health challenges
- Four studies advancing patient-centered CER methods, including strategies for meaningful engagement of patients and those who care for them
- Fifteen projects supporting implementation of PCORI-funded CER findings into real-world clinical settings
New research awards
The newly awarded patient-centered CER projects will compare different approaches to care across a broad set of health concerns. Studies will examine:
- Initial treatment options for people with painful diabetic neuropathy.
- Effectiveness and safety of antinausea medications during pregnancy.
- Advanced care planning interventions in primary care settings.
- Strategies to promote sleep and reduce delirium in intensive care unit settings.
- Dementia caregiving support approaches.
- Tobacco cessation in community mental healthcare settings.
- Interventions for adults and children with chronic kidney disease.
Two additional awards fund CER focused on trauma in adolescents. One study will compare strategies to increase adoption of evidence-based treatment for trauma and substance use. The other will compare approaches to treating trauma alongside other mental health concerns.
Four additional awards fund studies designed to strengthen the conduct of patient-centered CER. These include three focused on advancing CER methods and one focused on building the evidence base about effective engagement of patients and other healthcare decision makers through the design and conduct of patient-centered CER.
Accelerating uptake of PCORI-funded research results
To help ensure results generated by PCORI-funded CER are accessible and usable by health decision makers, PCORI funds implementation projects that help advance the adoption of high-priority evidence into real-world clinical settings. Through its Health Systems Implementation Initiative (HSII), PCORI has announced 15 new funding awards for projects focused on:
- Improving hypertension diagnosis and management.
- Electronic monitoring of patient-reported outcomes during cancer treatment.
- Expanding access to mental healthcare through telepsychiatry collaborative care.
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