Study maps how NF-κB regulates gene expression in cells

Dr. Gregory ReevesNF-κB is involved in several medically relevant cellular behaviors, such as inflammation, innate immunity and wound healing. This level of understanding could lead to the ability to control these cellular processes ourselves, because mistakes in NF-κB activity can lead to disease states, such as cancer."

Source:

Texas A&M University

Journal reference:

Dima, S. S., et al. (2026). Global maps of transcription factor properties reveal threshold-based formation of DNA-bound and mobile clusters. Science Advances. DOI: 10.1126/sciadv.ady3909. https://www.science.org/doi/10.1126/sciadv.ady3909