Rituximab alters T-cell metabolism in patients with nephrotic syndrome

The findings, published in iScience, identify a previously unknown link between B cells and T cells that could help predict how a patient with nephrotic syndrome will respond to RTX.

One drug, two cell types, different responses

Using public data on children with nephrotic syndrome, the researchers also found that T cells rely on a less efficient way of producing energy, and that disease-related B cells and T cells show abnormal communication with each other.

Towards a predictive test 

Source:

Nagoya University

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