Targeted antibody therapy provides long-lasting relief from neuropathic pain
· News-MedicalDr. Daisuke Uta, Associate Professor, University of ToyamaNaV1.7 is a specialized sodium ion channel in nerve cells that plays an important role in sensing and transmitting pain signals."
As the findings are still preclinical, the researchers were unable to accurately measure how much antibody reached the injured nerve. In addition, the treatment was evaluated in only one neuropathic pain model, highlighting the need for further studies to determine whether the findings can be replicated in other models. Nevertheless, the study provides preclinical evidence for a potential new strategy for treating neuropathic pain. Remarkably, the papers also report that S-151128, one of the antibodies studied, is currently in clinical trials, marking an important step towards determining whether the promising effects seen in animals can be used as a treatment for people.
Source:
Journal reference: