Experts outline a multidisciplinary approach to managing clinical obesity

GLP-1 receptor agonists have fundamentally changed the treatment landscape for obesity.
The commentary incorporates the emerging concept of clinical obesity, which recognizes obesity as a chronic, systemic disease and highlights the limitations of relying on body mass index alone to assess health risks.
Obesity care is increasingly moving toward a multidisciplinary model that combines medications, endoscopic therapies, and surgery.
New evidence supports endoscopic sleeve gastroplasty and other endoscopic bariatric and metabolic therapies as effective treatment options.
Advances in genetics and precision medicine may help physicians better match patients with obesity treatments that are most likely to be effective.
Combining GLP-1 medications with endoscopic or surgical interventions may produce greater and more durable weight loss than either approach alone.

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