Alumis (ALMS) vs. Its Rivals Head-To-Head Contrast

Alumis (NASDAQ:ALMS – Get Free Report) is one of 617 publicly-traded companies in the “MED – BIOMED/GENE” industry, but how does it weigh in compared to its rivals? We will compare Alumis to related companies based on the strength of its institutional ownership, dividends, risk, analyst recommendations, profitability, valuation and earnings.

Risk and Volatility

Alumis has a beta of -1.91, indicating that its stock price is 291% less volatile than the S&P 500. Comparatively, Alumis’ rivals have a beta of 0.90, indicating that their average stock price is 10% less volatile than the S&P 500.

Valuation and Earnings

This table compares Alumis and its rivals revenue, earnings per share (EPS) and valuation.

Alumis’ rivals have higher revenue and earnings than Alumis. Alumis is trading at a lower price-to-earnings ratio than its rivals, indicating that it is currently more affordable than other companies in its industry.

Profitability

This table compares Alumis and its rivals’ net margins, return on equity and return on assets.

Institutional and Insider Ownership

51.3% of shares of all “MED – BIOMED/GENE” companies are held by institutional investors. 40.7% of Alumis shares are held by insiders. Comparatively, 13.3% of shares of all “MED – BIOMED/GENE” companies are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Analyst Ratings

This is a summary of recent ratings and target prices for Alumis and its rivals, as provided by MarketBeat.

Alumis presently has a consensus target price of $20.40, indicating a potential upside of 106.27%. As a group, “MED – BIOMED/GENE” companies have a potential upside of 56.43%. Given Alumis’ stronger consensus rating and higher probable upside, equities research analysts clearly believe Alumis is more favorable than its rivals.

Summary

Alumis rivals beat Alumis on 7 of the 13 factors compared.

About Alumis

(Get Free Report)

Our mission is to significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies. Our name, Alumis, captures our mission to enlighten immunology, and is inspired by the words “allumer”-French for illuminate-and “immunis”-Latin for the immune system. We are a clinical stage biopharmaceutical company with an initial focus on developing our two Tyrosine Kinase 2 (TYK2) inhibitors: ESK-001, a second-generation inhibitor that we are developing to maximize target inhibition and optimize tolerability, and A-005, a central nervous system (CNS) penetrant molecule. ESK-001 has demonstrated significant therapeutic effect in our Phase 2 program in patients with PsO, which we define as moderate-to-severe plaque psoriasis (PsO), and is currently being evaluated in an additional Phase 2 clinical trial in patients with systemic lupus erythematosus (SLE), for which we expect to report results in 2026. With the favorable results in our Phase 2 clinical trial in PsO, we intend to initiate multiple Phase 3 clinical trials of ESK-001 in the second half of 2024 in this indication. TYK2 genetic mutations are associated with a strong protective effect in multiple sclerosis, motivating us to develop our second product candidate, A-005, as a CNS-penetrant, allosteric TYK2 inhibitor for neuroinflammatory and neurodegenerative diseases. In April 2024, we initiated our Phase 1 program of A-005 in healthy volunteers and expect to report initial results by the end of 2024. We utilize our proprietary precision data analytics platform, biological insights and team of experienced research and development experts to deepen our understanding of disease pathologies, accelerate research and development and increase the probability of clinical success. Our collective insights informed our selection of TYK2 as the target for our two lead programs. Beyond TYK2, our proprietary precision data analytics platform and drug discovery expertise have led to the identification of additional preclinical programs that exemplify our precision approach. We recognize that patients living with immune-mediated diseases need alternatives to currently available therapies. Despite recent advances and innovations in the treatment of immune-mediated diseases, many patients continue to suffer, cycling through currently approved therapies while looking for a solution that alleviates the debilitating impact of their disease without life-limiting side effects. Addressing the needs of these patients is why we exist. We are pioneering a precision approach that leverages insights derived from powerful data analytics to select the right target, right molecule, right indication, right patient, right endpoint and right combination to dramatically improve patient outcomes. We believe that combining our insights with an integrated approach to drug development will produce the next generation of treatments to address immune dysfunction. We were founded in January 2021 as a Delaware corporation under the name FL2021-001, Inc. We changed our name to Esker Therapeutics, Inc. in March 2021, and subsequently to Alumis Inc. in January 2022. Our principal executive offices are located at 280 East Grand Avenue, South San Francisco, California.