The Rajiv Gandhi Centre for Biotechnology (RGCB) has been selected as one of the four national next-generation sequencing (NGS) hubs for the Metagenomic Syndromic Surveillance Programme under the National ‘One Health Mission’ initiative, an official release said here on Thursday. The programme aims to address the long-standing challenge of undiagnosed acute febrile illness, encephalitis, diarrhoeal diseases, and respiratory infections. It enables the simultaneous detection of known, rare, and novel pathogens that traditional diagnostic pathways often miss.