College football odds, picks, lines, bets, predictions for Week 6, 2024: Computer model loves Iowa, California
SportsLine's advanced computer model has revealed its 2024 Week 6 college football picks
· CBS SportsThe No. 12 Ole Miss Rebels suffered a shocking defeat last week against the Kentucky Wildcats as double-digit favorites at home. The Rebels will face another stiff test in the SEC on Saturday when Lane Kiffin's squad travels to take on the South Carolina Gamecocks. According to the latest Week 6 college football odds via SportsLine consensus, Ole Miss is favored by 9.5 points on the road. Ole Miss is 10-2 in its last 12 games played in October, but should you back the Rebels in your Week 6 college football picks?
The only Top 25 matchup on Saturday also happens in the SEC when the No. 25 Texas A&M Aggies host the No. 9 Missouri Tigers at noon ET. Despite boasting an undefeated record, the Tigers are 2.5-point underdogs on the road. Will the Aggies, who list starting quarterback Conner Weigman (shoulder) as questionable, hand Missouri its first loss of the season, or will the Tigers leave Kyle Field undefeated? Before locking in any Week 6 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model.
The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks. It also went a sizzling 6-0 on all top-rated college football picks in Week 5. Anyone who has followed it has seen strong returns.
Now, it has turned its attention to the latest college football odds and Week 6 college football betting lines on the spread, money line and over/under. Head here to see every pick.
Top college football predictions for Week 6
One of the college picks the model is high on during Week 6: Iowa (+17.5) stays within the big spread at No. 3 Ohio State in a 3:30 p.m. ET matchup on Saturday. The Hawkeyes have one of the best running backs in college football. Junior Kaleb Johnson ranks second in the nation with 685 rushing yards on 82 carries. He's recorded nine rushing touchdowns and is coming off a stellar showing in Iowa's victory over Minnesota. Johnson finished last week's win with 21 carries for 206 yards and three scores.
In addition, Iowa is the most disciplined team in college football, having committed just 11 penalties through its first four games. Kirk Ferentz's team ranks first in the nation with 2.75 penalties per game. Defensively, the Hawkeyes are giving up only 62.0 rushing yards per game, a big reason why SportsLine's model has Iowa covering the spread well over 50% of the time. See the rest of its Week 6 college football picks here.
Another prediction: California (+10) plays a one-score game against No. 8 Miami in a 10:30 p.m. ET kickoff on Saturday. California has been an elite defensive team early in the season, ranked No. 12 in college football in points allowed per game (12.8). The Golden Bears have not allowed more than 14 points in any of their first four games, so they will provide a new test for Miami quarterback Cameron Ward.
On the other side of the ball, Cal's offense is facing a Hurricanes defense that gave up 34 points in a narrow win over Virginia Tech last week. Sophomore running back Jaivian Thomas has rushed for 267 yards on 38 carries, averaging 7.0 yards per attempt. The Golden Bears are 5-2 in their last seven home games, while Miami has only covered the spread four times in their last 17 conference games, so the model has California covering in nearly 60% of simulations. See picks for every other game in Week 6 here.
How to make college football picks for Week 6
The model has also made the call on who wins and covers in every FBS matchup in Week 6, and it's calling for a whopping seven underdogs to win outright. You can only get every pick for every game at SportsLine.
So what college football picks can you make with confidence, and which seven underdogs win outright in Week 6? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception, and find out.
College football odds for Week 6
See full Week 6 college football picks, odds, predictions here
Saturday, Oct. 5
Missouri at Texas A&M (-2.5, 47.5)
UCLA at Penn State (-28.5, 46.5)
Ole Miss at South Carolina (+9.5, 53.5)
Iowa at Ohio State (-17.5, 45.5)
Alabama at Vanderbilt (+22.5, 54.5)
Clemson at Florida State (+16.5, 46.5)
Tennessee at Arkansas (+14, 56.5)
Baylor at Iowa State (-11.5, 44.5)
Michigan at Washington (-1.5, 40.5)
Miami at California (+10, 54)
Texas Tech at Arizona (-6.5, 63.5)